Doi lab’s mission

My main research focus is on understanding the ways in which deregulation of the body clock (‘circadian clock’) drives development of human diseases. This is an extremely pressing matter, given the stresses that modern lifestyles exert on the circadian system, such as increased use of artificial light at night and the impact of shift work and ageing. As such, my laboratory is committed to developing pharmacological strategies that aim to realign or rejuvenate intrinsic timekeepers, and thereby act as therapeutic interventions against conditions associated with circadian misalignment such as cancer, obesity, and heart disease.